Lindsay Rosenwald’s History & Accomplishments

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Posted on 15th September 2011 by emorgan in Lindsay Rosenwald Info

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Biotechnology is an industry that is really taking off these days, and Dr. Lindsay Rosenwald is at the helm of its development. Dr. Rosenwald’s investment portfolio is diverse. He invests in companies devoted to various endeavors, from research to developments in drugs.

Dr. Lindsay Rosenwald has made a name for himself on Wall Street where he is a well-respected venture capitalist and hedge fund manager. He also has a long-lasting reputation in various fields of medicine and life-sciences research. In the arenas of healthcare and biotechnology, he is a leader, always at the forefront of R&D innovations. His singular experience combining the reaches of science with the power of finance has given Dr. Rosenwald the keen ability to create new avenues of research as well as find promising companies to invest in. His contributions are as countless as they are impacting. Millions of people across the world have benefited from healthcare that is, today, more far-reaching, a reality that Dr. Rosenwald has helped to create. There is hardly another person who can compare with the level of achievements Dr. Rosenwald has collectively made in these various fields.

In the progress of his brilliant career, spanning almost two decades, Dr. Lindsay A. Rosenwald, has established and re-capitalized many public and private life-science and biotech companies.

After finishing up high school at Abington in 1973, Rosenwald began his college career at Pennsylvania State University. He graduated with a degree in Finance. He continued his education at the Temple University School of Medicine and completed his internship at Abington Medical Hospital. Thereafter, Rosenwald sustained his own private practice in medicine before moving on to other horizons. On Wall Street, he combined his two expert subjects, finance and medicine, and carving his way, he continued to walk the path to success.

Between 1994 and 2007, Rosenwald played the role of executive director for the Aries Funds. The Funds invested over $1 billion into healthcare. From 2002 to 2006, Rosenwald took another executive position, at the head of the Orion Fund which specifically invested in biotechnology initiatives, especially private investments in public equity.

Dr. Rosenwald established a non-profit organization called the Rosenwald Foundation. The organization is devoted to supporting many scientific, healthcare and educational companies.

Rosenwald’s approach to medicine in conjunction with finance has encouraged him on his unique path. His approach allows him to pursue new angles in medicine, biotechnology and life sciences.

Dr. Rosenwald is currently a director at the Republican Jewish Coalition and also serves as president of Paramount Group. The Paramount Group’s specialty is in investment banking, R&D, and equity management in life-sciences and biotechnology. One of Dr. Rosenwald’s most recent undertakings is the OpusPoint Partners, LLC which was created in 2009. The new company’s aim is to offer support to promising endeavors and new accomplishments in life-sciences and biotechnology. OpusPoint Partners is committed to ground-breaking innovations and technologies in these industries.

Notable achievements by Dr. Lindsay Rosenwald and his team include providing funding for numerous companies and drug candidates that show promise. Cougar Biotechnology Inc., in L.A., is one of these companies. Its primary mandate is fighting cancer and has recently produced a new drug for aggressive forms of prostate cancer called Abiraterone. In 2009, Johnson & Johnson gained possession of this auspicious company for $1 billion after negotiating with Dr. Rosenwald.

Dr. Rosenwald and OpusPoint Partners will continue to seek opportunities for projects like this one. With these kinds of initiatives, they hope to change the face of medicine and life sciences, at the same time changing the rest of the world.

By establishing solid relationships and building upon their successes, OpusPoint Partners, along with Dr. Rosenwald’s leadership, will meet their goals. They already have an entire host of avant-garde credits to their name. Dr. Rosenwald is a truly innovative leader. He was the first investor in the first obesity drug in the US market. He was also the first founder of a stem cell company that trades publicly. The development of the first public gene therapy company owes its development to Dr. Rosenwald. Other accomplishments that Rosenwald has been involved in include the first cancer vaccine made available to the public.

Currently, Dr. Lindsay Rosenwald and OpusPoint Partners seek to create strong relationships with other leaders that share the same values and attitude to business and who are also passionate about finding and supporting breakthrough technologies.

With this level of determination, skill and methodology, OpusPoint Partners and its two founders, Dr. Rosenwald and Michael S. Weiss, have a broad and stable future ahead of them. The investments that they collectively make are bound to leave a very lasting impression on the way we look at disease.

Abiraterone Phase III Trial Compared with Provenge

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Posted on 12th January 2011 by emorgan in Lindsay Rosenwald Info

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During one of the recent Johnson & Johnson Phase III trials, the combination of abiraterone acetate and prednisone/prednisolone tested great as prostate cancer suppressants, contributing to a significant improvement in survival statistics. That prompted an independent data monitoring committee to reveal the data of the trial and to offer abiraterone to those participants, who were treated with a placebo.

Kellie McLaughlin, the company’s spokesman, officially confirmed that the company had achieved progress, and he said that it took a real breakthrough to allow termination of an interim trial. Reportedly, more than 1,000 patients, some with severe metastasis expansion and several aggressive chemotherapy courses behind, took part in a research, known as COU-AA-301. The trial was originally invested by leading investment banks, including BioSciences owned by Lindsay Rosenwald, MD.

Another study – COU-AA-302 – aimed at researching the conditions of patients with metastatic prostate cancer, is currently under way. It is being applied to patients who have not received chemotherapeutic treatment courses thus far. Instead, they are getting intensive abiraterone-prednisone treatment as a part of the anti-cancer research.

In his report for BioWorld Today, Kimberly Lee, a Hunter Global Securities analyst, is optimistic about the abiraterone Phase III and MDV-3100, considering more than satisfactory Phase II results and the drugs’ similar effects. However, there is another promising, FDA-approved drug, which is actually a pioneering anti-cancer drug in the U.S. – Dendreon Corp.’s Provenge (sipuleucel-1). Provenge has proven effective against metastatic prostate cancer. For this reason, the discinception of abiraterone is not expected to take any significant effect on Provenge sales. However, though neither abiraterone nor MDV3100 can compete with Provenge, it might be possible to combine these drugs. This is where additional investments will be very handy and Dr. Lindsay Rosenwald and his analysts already think about the possible funding of a new research. In any event, it will take additional research to evaluate the degree of risk posed by the use of Provenge – a potent immune stimulant – in combination with immune suppressants, which are normally used along with abiraterone.

According to David Hung, President and Chief Executive Officer of Medivation, theoretically, abiraterone can be used along with Provenge. In his report, he noted several properties of MDV3100, which ensure improvement in many separate aspects, and an improvement in overall survival statistics among patients, who have received Provenge treatment.

In partnership with Astellas Pharma Inc., Medivation continues the research on MDV3100 and has yet three major trials to complete. Involved in the studies will be patients with early-stage prostate tumors.

Johnson & Johnson acquired Cougar Biotechnology Inc. in July 2009, and thus purchased abiraterone. Cougar, Los Angeles, previously funded by Lindsay Rosenwald’s investment bank, is now J&J’s subsidiary operating in conjunction with Ortho Biotech Oncology Research & Development – a J&J affiliate group.

Abiraterone acetate was licensed by Cougar in 2004 from BTG plc of the UK. This license agreement permits BTG to outline marketing strategies and entitles it to royalties, providing the product is properly formulated and is granted sale permission.

Some analysts, such as Piper Jaffray, who are well aware of BTG marketing dynamics, predict abiraterone sales to reach $1.2 billion by 2018.

Dr. Lindsay Rosenwald- Researches and Inventions

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Posted on 3rd May 2010 by admin in Lindsay Rosenwald Info

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Dr. Lindsay Rosenwald is the one known till today by many people related to Biotechnology field due to his sacrifice and efforts to bring this area to such heights that it takes lots of time to one to begin. It is the Rosenwald who started to implement such companies which are know very successful and very popular. Out of these companies some of them are also related to financial investments. These are also the companies which are interlinked with the fields like Biotechnology and Life Sciences.

Dr. Lindsay Rosenwald can also be known to start companies which were the inventories to the new drugs that help the human life a lot by curing the diseases that affect human body by making them weak. Cougar Biotechnology and Polarx Biopharmaceuticals are the two most popularly known companies under the foundation of Rosenwald. These two companies invented two new drugs in addition to the older ones. Though these drugs are being developed by the companies under Rosenwald’s guidance they are being allowed to enter the market after few medical tests. Drugs are the one which are known scientifically as life Savers.

All the inventions and developments of the drugs are done by highly qualified people related to various fields of Biotechnology under scientific research. It can be said that the team is grouped in accordance to the experts who are highly skilled with the practical and theoretical knowledge. The formulation of the drug and its manufacturing are done in a process like technology transfer, pharmacology and toxicology aspects of the drug, clinical development, regulatory, marketing, etc. The sacrifices of these team members are valued with the success selling of their products in the market.

It is Dr. Lindsay Rosenwald was a person by whom many new young Biotechnologists where inspired and laid new ways to further success. Drugs under Rosenwald’s foundation helped to cure more deadly diseases which can be thought as the one having no treatment. Rosenwald was the one with two invaluable features which were both as per financial and physician analysts.

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